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Diabetic Kidney Problems

If you have diabetes, your blood glucose, or blood sugar, levels are too high. Over time, this can damage your kidneys. Your kidneys clean your blood. If they are damaged, waste and fluids build up in your blood instead of leaving your body.

Kidney damage from diabetes is called diabetic nephropathy. It begins long before you have symptoms. People with diabetes should get regular screenings for kidney disease. Tests include a urine test to detect protein in your urine and a blood test to show how well your kidneys are working.

If the damage continues, your kidneys could fail. In fact, diabetes is the most common cause of kidney failure in the United States. People with kidney failure need either dialysis or a kidney transplant.

You can slow down kidney damage or keep it from getting worse. Controlling your blood sugar and blood pressure, taking your medicines and not eating too much protein can help.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

Diabetic Nerve Problems

If you have diabetes, your blood glucose, or blood sugar, levels are too high. Over time, this can damage the covering on your nerves or the blood vessels that bring oxygen to your nerves. Damaged nerves may stop sending messages, or may send messages slowly or at the wrong times.

This damage is called diabetic neuropathy. Over half of people with diabetes get it. Symptoms may include:

  • Numbness in your hands, legs, or feet
  • Shooting pains, burning, or tingling
  • Nausea, vomiting, constipation, or diarrhea
  • Problems with sexual function
  • Urinary problems
  • Dizziness when you change positions quickly

Your doctor will diagnose diabetic neuropathy with a physical exam and nerve tests. Controlling your blood sugar can help prevent nerve problems, or keep them from getting worse. Treatment may include pain relief and other medicines.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

Hyperglycemia

What is blood glucose?

Blood glucose, or blood sugar, is the main sugar found in your blood. It is your body's primary source of energy. It comes from the food you eat. Your body breaks down most of that food into glucose and releases it into your bloodstream. When your blood glucose goes up, it signals your pancreas to release insulin. Insulin is a hormone that helps the glucose get into your cells to be used for energy.

For people with diabetes, your body doesn't make enough insulin, can't use it as well as it should, or both. Too much glucose stays in your blood and doesn't reach your cells.

What is hyperglycemia?

Hyperglycemia means high blood glucose. It most often affects people who have diabetes. When you have diabetes, your body doesn't make enough insulin or can't use it the right way. Too much glucose stays in your blood and doesn't reach your cells.

What causes hyperglycemia?

A key part of managing diabetes is controlling your blood glucose levels. To do this, you need to follow a diabetes meal plan and get regular physical activity. You might also need to take diabetes medicines. You have to balance all of these to keep your blood glucose at the right levels. But if you eat too much food or the wrong foods, don't take your medicines correctly, or don't get physical activity, you can get hyperglycemia. It can also happen if you are stressed or sick.

Less commonly, people who don't have diabetes can also get hyperglycemia. It can be caused by conditions that can affect insulin or glucose levels in your blood. They include problems with your pancreas or adrenal glands, certain medicines, and severe illnesses.

What are the symptoms of hyperglycemia?

The symptoms of hyperglycemia include:

  • Feeling thirsty
  • Feeling tired or weak
  • Headaches
  • Urinating (peeing) often
  • Blurred vision

If you are diabetic and you often have high blood glucose levels or the symptoms of hyperglycemia, talk with your health care team. You may need a change in your diabetes meal plan, physical activity plan, or diabetes medicines.

If you don't have diabetes and you are having these symptoms, see your provider to find out the cause and how to treat it.

What other problems can hyperglycemia cause?

If hyperglycemia is not treated, it can cause other problems. In people with diabetes, long-term hyperglycemia can lead to serious health problems (diabetes complications).

If your blood glucose levels get very high, you can develop diabetes-related ketoacidosis (DKA). It happens when your body doesn't have enough insulin to allow blood glucose into your cells for use as energy. Instead, your liver breaks down fat for fuel. This process produces acids called ketones. When too many ketones are produced too fast, they can build up to dangerous levels in your body. This can be life-threatening.

The symptoms of DKA may include:

  • Trouble breathing
  • Nausea or vomiting
  • Pain in your abdomen (belly)
  • Confusion
  • Feeling very tired or sleepy

If you have an an at-home test for ketones, check your ketone level every 4 to 6 hours when your blood glucose is very high or when you are having these symptoms. If the test shows that your ketones are moderate or high, or if you don't have a ketones test, contact your health care provider right away or get emergency medical help.

How is hyperglycemia diagnosed?

If you have diabetes, you'll most likely need to check your blood glucose every day and make sure that it's not too high. You can do this with a blood glucose meter or continuous glucose monitoring (CGM) system.

There are also blood tests that providers can use to check if your blood glucose is too high.

What are the treatments for hyperglycemia?

If you have diabetes and often have high blood glucose, your health care team may make changes to your diabetes meal plan, physical activity plan, and/or diabetes medicines.

If you have severe hyperglycemia and are having symptoms of DKA, you will need treatment at the hospital. The treatment often includes I.V. (intravenous) fluids and insulin.

Can hyperglycemia be prevented?

If you have diabetes, managing your diabetes can help prevent hyperglycemia. To manage your diabetes, it's important to:

  • Follow your diabetes meal plan
  • Get regular physical activity
  • If you need diabetes medicines, take them correctly
  • Regularly check your blood glucose level
  • Get regular checkups with your health care team

Hypoglycemia

What is blood glucose?

Blood glucose, or blood sugar, is the main sugar found in your blood. It is your body's primary source of energy. It comes from the food you eat. Your body breaks down most of that food into glucose and releases it into your bloodstream. When your blood glucose goes up, it signals your pancreas to release insulin. Insulin is a hormone that helps the glucose get into your cells to be used for energy.

For people with diabetes, your body doesn't make enough insulin, can't use it as well as it should, or both. Too much glucose stays in your blood and doesn't reach your cells.

What is hypoglycemia?

Hypoglycemia means low glucose. It happens when the level of glucose in your blood drops below what is healthy for you:

  • For many people with diabetes, this means a blood glucose level lower than 70 mg/dL. Your number might be different, so check with your health care team to find out what blood glucose level is too low for you.
  • For people who don't have diabetes, hypoglycemia is typically a blood glucose level lower than 55 mg/dL.
What causes hypoglycemia?

Hypoglycemia is common in people who have diabetes type 1 or who have diabetes type 2 and take insulin or other diabetes medicines. It can happen:

  • As a side effect of insulin or some other medicines that help your pancreas release insulin into your blood. These medicines can lower your blood glucose level.
  • If you don't eat or drink enough carbohydrates (carbs). Carbs are the main source of glucose for your body.
  • If you get a lot more physical activity than usual.
  • If you drink too much alcohol without enough food.
  • When you are sick and can't eat enough food or keep food down.

Although it's rare, you can still get low blood glucose without having diabetes. The causes can include conditions such as liver disease, kidney disease, and hormone deficiencies (lack of certain hormones). It can also happen in people who have had certain types of weight loss surgery. Some medicines, such as certain heart medicines and antibiotics, can also cause it. See your health care provider to find out the cause of your low blood glucose and how to treat it.

What are the symptoms of hypoglycemia?

The symptoms of low blood glucose tend to come on quickly. The symptoms can be different for everyone, but they may include:

  • Shaking
  • Sweating
  • Nervousness or anxiety
  • Irritability or confusion
  • Dizziness
  • Hunger
How is hypoglycemia diagnosed?

If you have diabetes, you'll most likely need to check your blood glucose every day and make sure that it's not too low. You can do this with a blood glucose meter or continuous glucose monitoring (CGM) system.

There are also blood tests that providers can use to check if your blood glucose is too low.

If you don't have diabetes and you have hypoglycemia, your provider will likely order other tests to try to figure out the cause.

What are the treatments for hypoglycemia?

If you have mild or moderate hypoglycemia, eating or drinking something with carbohydrates can help. But severe hypoglycemia can cause serious complications, including passing out, coma, or even death. Severe hypoglycemia can be treated with glucagon, a hormone that raises blood glucose levels. It can be given as nasal spray or injection. If you have diabetes, your provider can prescribe you a glucagon kit for use in case of an emergency.

If you have diabetes and you often have mild or moderate low blood glucose, your health care team may make changes to your diabetes meal plan, physical activity plan, and/or diabetes medicines.

If you don't have diabetes and you keep having low blood glucose, the treatment will depend on what is causing it to happen.

Can hypoglycemia be prevented?

If you have diabetes and you take insulin or other medicines that lower blood glucose, you can help prevent hypoglycemia if you:

  • Follow your diabetes meal plan. Eat and drink enough carbs to keep your blood glucose in your target range. Also carry a source of fast-acting carbohydrate, such as glucose tablets or a juice box, with you in case your blood glucose gets too low.
  • Be safe during physical activity. Check your blood glucose before and afterwards. You may need to eat a snack before your physical activity.
  • If you take diabetes medicines, make sure to take them correctly.

Prediabetes

What is prediabetes?

Prediabetes means that your blood glucose, or blood sugar, levels are higher than normal but not high enough to be called diabetes. Glucose comes from the foods you eat. Too much glucose in your blood can damage your body over time.

If you have prediabetes, you are more likely to develop type 2 diabetes, heart disease, and stroke. But if you make some lifestyle changes now, you may be able to delay or prevent type 2 diabetes.

What causes prediabetes?

Prediabetes usually happens when your body has a problem with insulin. Insulin is a hormone that helps the glucose get into your cells to give them energy. A problem with insulin could be:

  • Insulin resistance, a condition in which the body can't use its insulin properly. It makes it hard for your cells to get glucose from your blood. This can cause your blood sugar levels to rise.
  • Your body can't make enough insulin to keep your blood sugar levels at a healthy level

Researchers think that being overweight and not getting regular physical activity are major factors in causing prediabetes.

Who is at risk for prediabetes?

About 1 out of every 3 adults has prediabetes. It is more common in people who:

  • Are overweight or have obesity
  • Are age 45 or older
  • Have a parent, brother, or sister with diabetes
  • Are African American, Alaska Native, American Indian, Asian American, Hispanic/Latino, Native Hawaiian, or Pacific Islander American
  • Are not physically active
  • Have health conditions such as high blood pressure and high cholesterol
  • Have had gestational diabetes (diabetes in pregnancy)
  • Have a history of heart disease or stroke
  • Have metabolic syndrome
  • Have polycystic ovary syndrome (PCOS)
What are the symptoms of prediabetes?

Most people don't know they have prediabetes because usually there are no symptoms.

Some people with prediabetes may have darkened skin in the armpit or on the back and sides of the neck. They may also have many small skin growths in those same areas.

How is prediabetes diagnosed?

There are a few different blood tests that can diagnose prediabetes. The most common ones are:

  • Fasting plasma glucose (FPG) test, which measures your blood sugar at a single point in time. You need to fast (not eat or drink) for at least 8 hours before the test. The results of the test are given in mg/dL (milligrams per deciliter):
    • A normal level is 99 or below
    • Prediabetes is 100 to 125
    • Type 2 diabetes is 126 and above
  • A1C test, which measures your average blood sugar over the past 3 months. The results of an A1C test are given as a percentage. The higher the percentage, the higher your blood sugar levels have been.
    • A normal level is below 5.7%
    • Prediabetes is between 5.7 to 6.4%
    • Type 2 diabetes is above 6.5%
If I have prediabetes, will I get diabetes?

If you have prediabetes, you may be able to delay or prevent type 2 diabetes through lifestyle changes:

  • Losing weight, if you are overweight
  • Getting regular physical activity
  • Following a healthy, reduced-calorie eating plan

In some cases, your health care provider may also recommend taking diabetes medicines.

Can prediabetes be prevented?

If you are at risk for prediabetes, those same lifestyle changes (losing weight, regular physical activity, and a healthy eating plan) may prevent you from getting it.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

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